(2025) identified specific immune cell types linked to relapse risk in microscopic polyangiitis (MPA), a rare autoimmune disease causing blood vessel inflammation.
Researchers analyzed individual neutrophils and found two distinct groups in MPA patients: immature neutrophils and those with genes activated by type II interferon, a protein involved in immune responses.
The findings suggest tracking these cell types could help predict relapses, potentially enabling earlier treatment adjustments.
While more research is needed, this approach represents a step toward personalized care for MPA patients by focusing on their unique immune cell profiles (Nishide et al., 2025).